Rabbit Anti-GPX3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GPX3
IR:Immunogen Range:1-100/226
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2878
Swiss Prot:P22352
Source:KLH conjugated synthetic peptide derived from human GPX3:1-100/226
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Glutathione peroxidases(Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organichydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPxfamily to be discovered. GPx2, also known as gastrointestinal GPx(GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract.Extracellular plasma GPx(pGPxor GPx3) is mainly expressed by the kidney from where it is released into the blood. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxylipids in low density lipoprotein orthymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site
Size:50ul
Concentration:1mg/ml
Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： GPX3;Extracellular glutat;GPX 3;GPx P;GPx-3;GPX3;GPXP;GPX3_HUMAN;
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