Rabbit Anti-ASC/TMS1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ASC/TMS1
IR:Immunogen Range:50-195
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:29108
Swiss Prot:Q9ULZ3
Source:Recombinant human ASC:50-195
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. Tissue specificity: Widely expressed at low levels. Detected in peripheral blood leukocytes, lung, small intestine, spleen, thymus, colon and at lower levels in placenta, liver and kidney. Very low expression in skeletal muscle, heart and brain. Detected in the leukemia cell lines HL-60 and U937, but not in Jurkat T-cell lymphoma and Daudi Burkitt's lymphoma.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： ASC/TMS1;TMS1;ASC;CARD;PYCARD;MGC10332; TMS-1;ASC_HUMAN;
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