Mouse Anti-PIK3R1 (animal-free) Monoclonal Antibody
DATASHEET
Host:Mouse
Target Protein:PIK3R1 (animal-free)
IR:Immunogen Range:1-110/724
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:18708
Swiss Prot:P27986
Source:Recombinant mouse PI3K p85 Protein:1-110/724
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： PIK3R1 (animal-free);GRB1;PI3-kinase regulator;PI 3-kinase p85α; PI 3-kinase p85-α;IMD36;p85-ALPHA;SH3_PI3K_p85alpha;
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