Rabbit Anti-phospho-STAT6 (Tyr641) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-STAT6 (Tyr641)
IR:Immunogen Range:RG(p-Y)V
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6778
Swiss Prot:P42226
Source:KLH conjugated Synthesised phosphopeptide derived from human STAT6 around the phosphorylation site of Tyr641:RG(p-Y)V
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Also known as: signal transducers and activators of transduction 6; D12S1644; IL 4 STAT; IL4 STAT; Interleukin 4 Induced; Interleukin 4 Induced Transcription Factor IL4 STAT; Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced; Signal Transducer And Activator Of Transcription 6 Nirs Variant 1; STAT 6; STAT interleukin4 induced; STAT6B; STAT6C; Transcription factor IL 4 STAT.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： phospho-STAT6 (Tyr64;STAT6 (phospho Y641);p-STAT6 (phospho Y64;D12S1644 IL 4 STAT; IL4 STAT;STAT6B;STAT6C;Transcription factor;
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