Rabbit Anti-CD38 Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CD38
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:952
Swiss Prot:P28907
Source:Recombinant human CD38:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:100-200)
Flow-Cyt(1:100)
ICC(1:50)
Cross Reactive Species:Human
"仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CD38;ADP-ribosyl cyclase/;ADP-ribose hydrolase;cADPr hydrolase 1;2'-phospho-ADP-ribos;ADPRC 1;ADP-ribosyl cyclase ;CD38_HUMAN;
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