Product Name:[D-Ala2]-GIP (human)
CAS No.:444073-04-5
Synonyms:GIP受体激动剂[D-Ala2]-GIP (human)
Catalog No.:147P02
Brand:HongTide(上海鸿肽生物)
Description:[D-Ala2]-GIP (human)是一种高效的GIP受体激动剂多肽,序列中含有42个氨基酸,其EC50为630±119 pM。在表达野生型GIP受体的细胞中,与天然GIP相比,显示出等效的cAMP刺激特性和更高的酶降解抗性。改善各种肥胖和糖尿病动物模型的葡萄糖耐量、胰岛素释放和认知功能。在 PD 的 MPTP 模型中显示神经保护作用。
[D-Ala2] - GIP (human) is an efficient GIP receptor agonist peptide with a sequence containing 42 amino acids and an EC50 of 630 ± 119 pM. In cells expressing wild-type GIP receptors, they exhibit equivalent cAMP stimulation characteristics and higher enzymatic degradation resistance compared to natural GIP. Improve glucose tolerance, insulin release and cognitive function in various animal models of obesity and diabetes. Display neuroprotective effects in the MPTP model of PD.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Y-d-A-EGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ |
Sequence(3-letter code) | H-Tyr-D-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH |
Peptide Structure | ![[D-Ala2]-GIP (human) 444073-04-5.png [D-Ala2]-GIP (human) 444073-04-5.png](/SupplyImg/2023-08-15/6382773090094747164462303.jpg)
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Molecular Formula | C226H338N60O66S1 |
Molecular Weight | 4983.61 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: [D-Ala2]-GIP (human);444073-04-5;GIP受体激动剂[D-Ala2]-GIP;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。