Product Name:MAIT 203
CAS No.:N/A
Synonyms:环戊丙氨酸衍生拟肽MAIT 203
Catalog No.:218P467
Brand:HongTide(上海鸿肽生物)
Description:MAIT-203是一种环戊丙氨酸衍生的拟肽,序列中含有21个氨基酸,有效抑制腺瘤性息肉病 (APC)和Asef (RhoGEF4) 的相互作用,但不抑制 APC-Sam68 或 APC-striatin 的相互作用。MAIT-203 结合 APC-ARM,Ki 值为 0.015 μM,Kd 值为 0.036 μM。MAIT-203显着抑制结直肠癌细胞的迁移和侵袭。
MAIT-203 is a cyclic alanine derived peptide with 21 amino acids in its sequence, which effectively inhibits the interaction between adenomatous polyposis (APC) and Asef (RhoGEF4), but does not inhibit the interaction between APC-Sm68 or APC-striatin. MAIT-203 combined with APC-ARM, with a Ki value of 0.015 μ M. Kd value is 0.036 μ M. MAIT-203 significantly inhibits the migration and invasion of colorectal cancer cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Z-AGEA-Cpa-YEGGGGGRKKRRQRRR-NH2 |
Sequence(3-letter code) | Cbz-Ala-Gly-Glu-Ala-Cpa-Tyr-Glu-Gly-Gly-Gly-Gly-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2 |
Peptide Structure |
|
Molecular Formula | C106H177N43O29 |
Molecular Weight | 2517.83 |
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上海鸿肽生物科技有限公司
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关键字: 环戊丙氨酸衍生拟肽MAIT 203;MAIT 203;环戊丙氨酸衍生拟肽;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。