盐酸洛贝林，Α-洛贝林盐酸盐，洛贝林盐酸盐，盐酸山梗碱，山梗烷醇酮盐酸盐，原料，134-63-4

中文名称

盐酸洛贝林中文同义词Α-洛贝林盐酸盐;2-[6-(2-羟基-2-苯乙基)-1-甲基-2-呱啶基]-1-苯乙酮盐酸盐;(-)-洛贝林盐酸盐;盐酸-L-山梗碱;盐酸洛贝林/盐酸山梗碱;洛贝林盐酸盐;山梗菜碱盐酸盐;山梗烷醇酮盐酸盐英文名称alpha-Lobelinehydrochloride英文同义词(-)-id;2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor;2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone;Lobelinhydrochloride;2-((2R,6S)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone;LobelinHydrochlorde;2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONEHCL;2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONEHYDROCHLORIDECAS号134-63-4分子式C22H28ClNO2分子量373.92EINECS号205-150-2

盐酸洛贝林性质

熔点183-185°C(dec.)(lit.)比旋光度D20-43°(c=2)折射率-57.5°(C=1,H2O)储存条件Inertatmosphere,RoomTemperature溶解度H2O:25Chemicalbookmg/mL形态powder颜色whitetooff-white旋光性(opticalactivity)[α]20/D56.8°,c=2inH2OMerck14,5551BRN3920196LogP3.610(est)

用途盐酸洛贝林为反射性呼吸中枢兴奋药。由于刺激颈动脉体及主动脉弓化学感受器，反射性地兴奋延髓呼吸中枢，对迷走神经中枢和血管运动Chemicalbook中枢也同时有反射性的兴奋作用；对植物神经节先兴奋而后阻断。用于各种原因引起的呼吸抑制。常用于新生儿窒息，一氧化碳、阿片中毒等。