Product Name:Huwentoxin XVI
CAS No.:1600543-88-1
Synonyms:止痛剂多肽Huwentoxin XVI
Catalog No.:218P489
Brand:HongTide(上海鸿肽生物)
Description:Huwentoxin XVI是一种来自鸟蛛 Ornithoctonus huwena 的止痛剂多肽,序列中含有39个氨基酸,包含三对二硫键,是一种高度可逆和选择性的哺乳动物 N 型钙通道 (N-type calcium channel) (IC50 约为 60 nM) 拮抗剂。Huwentoxin XVI 对电压门控的 T 型钙通道,钾通道或钠通道没有影响。
Huwentin XVI is a pain relieving peptide derived from Ornithoctonus huwena, which contains 39 amino acids and three pairs of disulfide bonds. It is a highly reversible and selective mammalian N-type calcium channel (IC50 is approximately 60 nM) antagonist. Huwentin XVI has no effect on voltage gated T-type calcium channels, potassium channels, or sodium channels.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | CIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK (Disulfide bridge: 1-16,8-21,15-36) |
Sequence(3-letter code) | H-Cys-Ile-Gly-Glu-Gly-Val-Pro-Cys-Asp-Glu-Asn-Asp-Pro-Arg-Cys-Cys-Ser-Gly-Leu-Val-Cys-Leu-Lys-Pro-Thr-Leu-His-Gly-Ile-Trp-Tyr-Lys-Ser-Tyr-Tyr-Cys-Tyr-Lys-Lys-OH(Disulfide bridge:Cys1-Cys16;Cys8-Cys21;Cys15-Cys36) |
Peptide Structure |
|
Molecular Formula | C196H292N50O56S6 |
Molecular Weight | 4437.14 |
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关键字: 1600543-88-1;Huwentoxin XVI ;止痛剂多肽Huwentoxin XVI;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。