中文名：N,N,2-三甲基-5-硝基苯磺酰胺
英文名：N,N,2-Trimethyl-5-nitrobenzenesulfonamide
英文别名：433695-36-4|BRL-50481|BRL 50481|N,N,2-trimethyl-5-nitrobenzenesulfonamide|5-Nitro-2,N,N-trimethylbenzenesulfonamide|N,N,2-Trimethyl-5-nitro-benzenesulfonamide|Benzenesulfonamide, N,N,2-trimethyl-5-nitro-|BRL50481|CHEMBL484928|N,N,2-trimethyl-5-nitrobenzen
纯度：≥98%
货号：B137236
包装：250mg、50mg、10mg
Cas号：433695-36-4
存储温度：2-8°C储存
产品介绍：
BRL-50481 is a selective inhibitor of phosphodiesterase 7 (PDE 7) that has acceptable selectivity for in vitro studies. Studies sμggest that BRL-50481 is used to inhibit the activity of hrPDE7A1 which is usually expressed in baculovirus-infected Spodoptera frμgiperda in a competitive manner. In osteoblasts, BRL-50481increases mineralization and bALP as a result of PDE7 silencing which upregulates several osteogenic genes. Further studies show that BRL-50481increases apoptosis in CLL cells via a mitochondrial-dependent process, and is associated with increased cAMP accumulation and down-regulation of the antiapoptotic protein survivin. BRL-50481 is a inhibitor of PDE7A.
查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/B137236.html
关键字： 433695-36-4;BRL-50481;BRL 50481;N,N,2-trimethyl-5-nitrobenzenesulfonamide
上海阿拉丁生化科技股份有限公司是A股上市公司（（股票代码：688179），专注于科研试剂的研发、生产和销售，已陆续建立多个工厂和研发中心。作为领军企业，阿拉丁始终坚持质量第一，连续13年被评为“最受欢迎试剂品牌”。
阿拉丁目前常备库存试剂产品品种超过7万种，SKU总数超过46万，产品线涵盖了化学试剂、生化试剂、药靶配体、蛋白质和抗体等多个领域，是国内少数化学试剂到生物试剂全面发展的国产试剂品牌，产品同步发布在我们国内（www.aladdin-e.com）和海外（www.aladdinsci.com）电商平台。