中文名:阿戈美拉汀
英文名:Agomelatine
中文别名:N-[2-(7-甲氧基-1-萘基)乙基]乙酰胺
英文别名:Agomelatine|138112-76-2|Thymanax|Valdoxan|N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide|N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide|S20098|S-20098|Agomelatine [INN]|Melitor|AGO-178|S 20098|Acetamide, N-[2-(7-methoxy-1-naphthalenyl)ethyl]-|N-(2-(7-meth
纯度:≥98%(HPLC)
货号:A124691
包装:25mg、5mg、250mg
Cas号:138112-76-2
存储温度:2-8°C储存
产品介绍:
Agomelatine is an extremely potent agonist at both melatonin receptors (MT1 and MT2), with additional antagonism at 5HT2C. It is a novel antidepressant with many desired in vivo properties, including neuroprotection and neurogenesis in depression-sensitive brain areas. Agomelatine′s efficacy appears to be due to both melatonergic and serotonergic properties. In neurogenesis assays, both in vitro and in vivo, the compound effects were differentially affected by antagonists for MT1/MT2 and 5HT2C, demonstrating actions throμgh all three receptors.
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