中文名:溴丙酮酸
英文名:Bromopyruvic acid
中文别名:3-溴丙酮酸
英文别名:AS-16146|B1153|3-bromopyruvic acid|bromo-2-oxopropanoic acid|bromopyruvic acid|Bromopyruvic acid, >=97.0% (T)|J-650255|3-bromopyruvate|BPV|CS-5517|J-511892|3-bromo-2-oxopropanoic acid|AKOS015892643|AM84337|EINECS 214-206-5|3-BP|3-BrPA|SCHEMBL8126|Z1079181
纯度:96%
货号:B120321
包装:25g、5g、100g
Cas号:1113-59-3
产品介绍:
3-Bromopyruvic acid is a brominated derivative of pyruvic acid , which inhibits HXK II (hexokinase II) in cancer cells. As a result of this inhibition the cells are unable to metabolize glucose into ATP directly. Studies conducted on MCF-7 breast cancer cells show that 3-Bromopyruvic acid hydrate reduces the expression of Bcl-2, c-Myc and mutant p53, which are involved in the cell death signal transduction pathway. Alternate studies indicate that 3-Bromopyruvic acid hydrate is a very selective antibiotic, inhibiting the growth of certain yeasts.半胱氨酸残基的亲和标记;核酸和蛋白质之间的交联剂
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