中文名:1-甲基腺苷
英文名:1-Methyladenosine
英文别名:1-Methyladenosine|15763-06-1|N1-Methyladenosine|CHEBI:16020|Adenosine, N,6-didehydro-1,6-dihydro-1-methyl-|Adenosine, 1-methyl-|(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol|1-methyl Ado|NSC 92165|N(1)-methyladenosine|Aden
纯度:≥98%
货号:M303015
包装:50mg、100mg、10mg
Cas号:15763-06-1
存储温度:-20°C储存,充氩
产品介绍:
Product Describtion:
1-Methyladenosine, also known as M1A, belongs to the class of organic compounds known as purine nucleosides. Purine nucleosides are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety. 1-Methyladenosine is a strong basic compound (based on its pKa). Precise m6A mapping by m6A-CLIP/IP (briefly m6A-CLIP) revealed that a majority of m6A locates in the last exon of mRNAs in multiple tissues/cultured cells of mouse and human, and the m6A enrichment around stop codons is a coincidence that many stop codons locate round the start of last exons where m6A is truly enriched. The methylation of adenosine is directed by a large m6A methyltransferase complex containing METTL3 as the SAM-binding sub-unit. Insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1–3) are reported as a novel class of m6A readers.
Product Application:
Metabolomics
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关键字: 1-Methyladenosine;15763-06-1;N1-Methyladenosine;CHEBI:16020
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