中文名:硫藤黄素
英文名:Thiolutin
英文别名:Thiolutin|87-11-6|Acetopyrrothin|Acetopyrrothine|NSC3927|N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide|3-Acetamido-5-methylpyrrolin-4-one(4,3-d)-1,2-dithiole|NSC-3927|Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrr
纯度:95%
货号:T102393
包装:5mg、1mg、25mg
Cas号:87-11-6
存储温度:-20°C储存
产品介绍:
Thiolutin is an RNA polymerase inhibitor, and a sulfur-based microbial antibiotic generated by Streptomyces sp. The compound has been shown to inhibit transcription in Saccharomyces cerevisiae and mRNA degradation. Thiolutin inhibits the adhesion of endothelial cells, including adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin, and restricts tumor cell-induced angiogenesis. Studies have reported that Thiolutin is an effective inducer of HSP 27 (heat shock protein 27; Hsp27) phosphorylation. Research shows that in the presence of Thiolutin, the interaction between Hsp27 and nestin is disrupted, which results in the breakdown of nestin filaments.An RNA polymerase inhibitor and suppressor of tumor cell-induced angiogenesis
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关键字: Thiolutin;87-11-6;Acetopyrrothin;Acetopyrrothine
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