aladdin 阿拉丁 F135375 烟曲霉素 23110-15-8 98%

中文名：烟曲霉素

英文名：Fumagillin

英文别名：fumagillin|23110-15-8|Fugillin|Fumidil|Fumagillinum|Fumagilina|Fumagilline|(-)-Fumagillin|Fumagillina|Amebacilin|Fumagillin DCH|ZGN-201|Amebacillin|Fugilin|CCRIS 9025|DTXSID7040736|UNII-7OW73204U1|CHEBI:48635|NSC 9168|NSC-9168|EINECS 245-433-8|2,4,6,8-Dec

纯度：98%

货号：F135375

包装：1mg、25mg、5mg

Cas号：23110-15-8

存储温度：-20°C储存,充氩

产品介绍：

Fumagillin is a complex natural product antibiotic which covalently binds a key histidine residue of methionine aminopeptidase type II (MetAP-2), inhibiting endothelial cell proliferation and angiogenesis.An angiogenesis suppressing antibiotic and MetAP-2 inhibitor.It is an effective treatment for intestinal microsporidiosis caused by Enterocytozoon bieneusi. Used to treat the Nosema disease in honey bees. Applied topically to the conjunctiva in the treatment of microsporidial keratoconjunctivitis. The Research grade Fumagillin is used in the angiogenesis research. In the connection to its anti angiogenetic capabilities, Fumagillin is mentioned as an potential anti-neoplastic antibiotic;Fumagillin is a starting material for several anticancer drμg candidates, such as TNP-470, also shown to be able to protect macrophages from the HIV infection

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