中文名:阿米洛利盐酸盐水合物
英文名:Amiloride hydrochloride hydrate
中文别名:盐酸阿米洛利
英文别名:AMILORIDE HYDROCHLORIDE|2016-88-8|Amiloride HCL|Amiloride chloride|Amiloride HCl anhydrous|Amiloride (hydrochloride)|Amiloride hydrochloride anhydrous|MK-870 hydrochloride|Amiloride hydrochloride hydrate|N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide h
纯度:≥98%
货号:A131615
包装:1g、5g
Cas号:2016-88-8
存储温度:-20°C储存
产品介绍:
Amiloride ? HCl is a selective T-type calcium channel protein inhibitor that has been shown to inhibit the Polycystin-L channel (Polycystic kidney disease 2-like 1 protein: PKD2L1), a member of the transient receptor potential (TRP) superfamily of cation channels, including the NHE (sodium/hydgrogen exchanger). Amiloride is also an epithelial sodium channel protein inhibitor, which inhibits sodium reabsorption without affecting potassium concentrations. Amiloride serves as a non-selective acid-sensing ion channel (ASIC) blocker and a selective inhibitor of uPA (urokinase plasminogen activator). Research shows that amiloride reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 μM. Amiloride ? HCl is an inhibitor of Sodium/Potassium-ATPase Protein.A calcium channel andsodium channel protein inhibitor
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