中文名:盐酸西那卡塞
英文名:Cinacalcet HCl
中文别名:盐酸西那卡塞|盐酸甲状旁腺激素|N-((1R)-1-(1-萘基)乙基)-3-(3-(三氟甲基)苯基)丙-1-胺盐酸盐
英文别名:Cinacalcet hydrochloride|364782-34-3|Cinacalcet HCl|Sensipar|Mimpara|Regpara|(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride|AMG073 HCl|AMG-073 HCL|AMG073 hydrochloride|Cinacalcet hydrochloride [USAN]|Cinacalcet
纯度:≥99%
货号:C129866
包装:10mg、250mg、50mg
Cas号:364782-34-3
存储温度:-20°C储存
产品介绍:
Cinacalcet Hydrochloride is a type II calcimimetic agent which controls calcium levels in cells by allosteric activation of CaSR (calcium sensing receptors). Studies show that Cinacalcet Hydrochloride affects cell proliferation in CHO cells transfected with CaSRs. In addition, it is known that Cinacalcet Hydrochloride inhibits the secretion of the parathyroid hormone (PTH). These studies sμggest that Cinacalcet Hydrochloride in instrumental in increasing the cytoplasmic concentration of Ca2+. Furthermore, Cinacalcet Hydrochloride is an analog of NPS R-568 which contains a much better metabolic profile.An allosteric activator of CaSR
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