中文名:普罗地芬 盐酸盐
英文名:SKF-525A Hydrochloride
中文别名:盐酸丙基解痉素|SKF-525A
英文别名:Proadifen hydrochloride|62-68-0|Proadifen HCl|Propyladiphenin|SKF-525A hydrochloride|Proadifen (hydrochloride)|SK&F 525-A|RP 5171|SKF 525A|Proadifen hydrochloride [USAN]|PROADIFENHYDROCHLORIDE|2-(diethylamino)ethyl 2,2-diphenylpentanoate hydrochloride|2-(
纯度:10mM in DMSO
货号:S425181
包装:1ml
Cas号:62-68-0
存储温度:-80℃储存
产品介绍:
SKF-525A HCl (Proadifen) has many biochemical functions, some of which include: inhibitory effects on NOS1 (neuronal nitric oxide synthase; IC50 = 90 mM), adult mouse skeletal muscle AChR (acetyl choline receptor), hepatic drug metabolism via the CYP (cytochrome P450) system, CYP-dependent (cytochrome P450-dependent) arachidonate metabolism (90% at 50 μM), transmembrane calcium influx, and platelet thromboxane synthesis. This compound has also been shown to block KIR6.1 (ATP-sensitive inward rectifier potassium channel 8; IC50 = 4.4 mM) and stimulate endothelial cell prostacyclin production.
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