Description
Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. CD142, also known as ,Coagulation Factor III, and Thromboplastin, is a 45 kD type I transmembrane glycoprotein. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis, atherosclerosis, and cancer. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells (cytoplasmic inclusions), astrocytes, myocardium, liver stromal cells, pancreas cells, and is also expressed on activated monocytes and stimulated endothelial cells.
Catalog No.
EHD00601
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Purity
>90% as determined by SDS-PAGE.
Applications
SDS-PAGE,WB,ELISA,Immunogen,Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Expression system
Mammalian cells
Accession
P13726
Protein length
Met1-Glu251
Nature
Recombinant
Predicted molecular weight
29.24 kDa
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Alternative Names
Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF, Drug Target
Species
Human
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Note
For research use only.
关键字: EHD00601;Human ;CD142/F3/TF;
武汉佰乐博生物(Biolab?Reagents)由一群具有二十年工作经验的生命科学领域顶级研究者创立于2021年,凭借丰富的产品开发经验,利用全球领先的技术平台,引进和整合全球高品质的蛋白、抗体和试剂盒产品。目前,佰乐博生物作为法国AntibodySystem和ProteoGenix在亚洲的独家总代理,提供近30,000种生命科学试剂,核心产品涵盖蛋白、抗体和试剂盒,旨在为科研工作者提供专业、全面、可靠的试剂支持,推动生命科学研究的深入发展。