Cadherin-17产品信息
英文名称:Cadherin-17
中文名称:钙粘蛋白17
靶点别称:Cadherin-17,CDH17,HPT-1,LI-cadherin
物种:Human / Mouse / Cynomolgus / Rat
属性:Protein / Antibody Licen0sing
标记:Biotin-labeled / Unconjugated
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150mM NaCl, pH8.0 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
Cadherin-17分子背景
Cadherin-17,也称为肝肠钙粘蛋白,属于钙依赖性细胞粘附分子钙粘蛋白家族。体内研究表明,CDH17敲除通过激活半胱氨酸天冬氨酸蛋白酶-3活性导致凋亡性PC肿瘤死亡。综上所述,CDH17通过调节肿瘤凋亡信号通路作为对PC生长至关重要的致癌分子发挥作用,并且CDH17可以作为开发抗PC治疗方法的靶点。
Cadherin-17用户评价
关键字: CDH17;CDH17蛋白;Cadherin-17蛋白;Cadherin-17;钙粘蛋白17;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。