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Vitronectin产品信息
英文名称:Vitronectin
中文名称:玻连蛋白
靶点别称:VTN,V75,VN,Vitronectin,S-protein,Serum-spreading factor
物种:Human
标签:Tag Free
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human Vitronectin Protein, Tag Free (VIN-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Leu 478 (Accession # P04004 ).
Predicted N-terminus: Asp 20
蛋白结构(Molecular Characterization)
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This protein carries no "tag".
The protein has a calculated MW of 52.3 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
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Vitronectin分子背景
Vitronectin也被称为S蛋白、VN、VTN、V75。Vitronectin是一种多功能糖蛋白,参与凝血、抑制膜攻击复合物(MAC)的形成、细胞粘附和迁移、伤口愈合和组织重塑。玻连蛋白的主要细胞来源是肝细胞。特异性抗血清或基因缺失阻断Hic(肺炎球菌表面蛋白C(PspC)家族的成员)分别显著降低了肺炎球菌与可溶性和固定化玻连蛋白以及因子H的结合。此外,Vitronectin与糖胺聚糖和蛋白多糖相互作用。被整合素家族的某些成员识别,并作为细胞与底物的粘附分子。末端溶细胞补体途径膜损伤作用的抑制剂。
关键字: Vitronectin;Vitronectin蛋白;玻连蛋白;VTN蛋白;VTN重组蛋白;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。