Product Name:ω-Conotoxin MVIIC
CAS No.: 147794-23-8
Synonyms:钙离子亚型通道多肽OMEGA-CONOTOXIN MVIIC
Catalog No.:211P13
Brand:HongTide(上海鸿肽生物)
Description:ω-Conotoxin MVIIC是具有抑制扑入哺乳动物中枢神经系统中的其他钙离子亚型通道的多肽,序列由26个氨基酸组成,序列中的6个Cys形成了三对二硫键,多肽结构相当稳定。ω-Conotoxin MVIIC序列中有四个Lys,但由于β-折叠的存在,导致侧链基团被包裹在序列中,因此多肽对生物素化的反应性很多,对生物活性的影响较小,因此ω-Conotoxin MVIIC具有成为药物原料的潜能非常巨大。
ω- Conotoxin MVIIC is a peptide that inhibits other calcium ion subtype channels that enter the central nervous system of mammals. The sequence consists of 26 amino acids, and the 6 Cys in the sequence form three pairs of disulfide bonds. The peptide structure is quite stable. ω- There are four Lys in the Conotoxin MVIIC sequence, but due to β- The presence of folding leads to the side chain groups being encapsulated in the sequence, resulting in a high reactivity of peptides towards biotinylation and a relatively small impact on biological activity. Therefore ω- Conotoxin MVIIC has enormous potential as a pharmaceutical raw material.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | CKGKGAPCRKTMYDCCSGSCGRRGKC-NH2(Disulfide bridge:Cys1-Cys16;Cys8-Cys20;Cys15-Cys26) |
Sequence(3-letter code) | H-Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH2(Disulfide bridge:Cys1-Cys16;Cys8-Cys20;Cys15-Cys26) |
Peptide Structure |
|
Molecular Formula | C106H178N40O32S7 |
Molecular Weight | 2749.25 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 钙离子亚型通道多肽OMEGA-CONOT;ω-Conotoxin MVIIC;147794-23-8;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。