Product Name:Amyloid β Peptide (42-1)(human)
CAS No.:317366-82-8
Synonyms:Amyloid beta (42-1) human;Amyloid b-Protein (42-1);淀粉样蛋白42-1
Catalog No.:107P66
Brand:HongTide(上海鸿肽生物)
Description:阿尔茨海默症(Alzheimer disease;AD)患者的大脑中,老人斑是最显著的病理特征之一,是不溶性蛋白质异常聚集形成丰富的β片层结构的淀粉样纤维,并积累于脑实质细胞间隙的构成物。早期的研究证实老人斑的主要构成成分为β-淀粉样蛋白多肽(Aβ),是由42个氨基酸组成的多肽,Amyloid β Peptide (42-1)(human)是Amyloid β Peptide (1-42)(human)的同分异构体。
In the brain of patients with Alzheimer's disease (AD), senile plaques are one of the most prominent pathological features, which are formed by abnormal aggregation of insoluble proteins and rich accumulation β The amyloid fibers with a layered structure accumulate in the interstitial spaces of brain parenchymal cells. Early studies have confirmed that the main components of senile plaques are β- Starch like protein peptide (A β), It is a peptide composed of 42 amino acids, Amyloid β Peptide (42-1) (human) is Amyloid β Isomers of Peptide (1-42) (human).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | AIVVGGVMLGIIAGKNSGVDEAFFVLKQHHVEYGSDHRFEAD |
Sequence(3-letter code) | H-Ala-Ile-Val-Val-Gly-Gly-Val-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-Gly-Val-Asp-Glu-Ala-Phe-Phe-Val-Leu-Lys-Gln-His-His-Val-Glu-Tyr-Gly-Ser-Asp-His-Arg-Phe-Glu-Ala-Asp-OH |
Peptide Structure | ![Amyloid β Peptide (42-1)(human) 317366-82-8.png Amyloid β Peptide (42-1)(human) 317366-82-8.png](/SupplyImg/2024-02-28/6384473049562551298498012.jpg)
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Molecular Formula | C203H311N55O60S1 |
Molecular Weight | 4514.11 |
订购联系方式:
上海鸿肽生物科技有限公司
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QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: Amyloid β Peptide (4;317366-82-8;淀粉样蛋白42-1;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。