Product Name:AF11377
CAS No.:171492-13-0
Synonyms:细胞因子(cytokine)拮抗剂多肽
Catalog No.:166P07
Brand:HongTide(上海鸿肽生物)
Description:AF11377是由15个氨基酸组成的直链多肽。AF11377可以阻碍 IL-1α 结合到 I 型 IL-1 受体上,其IC50值为1.9 nM。AF11377可以阻碍人和猴细胞中 IL-1-驱动的响应。AF11377是第一个高亲和力多肽结合到细胞因子受体(cytokine receptor)从而作为细胞因子(cytokine)拮抗剂的例子。
AF11377 is a linear peptide composed of 15 amino acids. AF11377 can hinder IL-1 α When bound to type I IL-1 receptors, its IC50 value is 1.9 nM. AF11377 can hinder the response of IL-1- driven cells in humans and monkeys. AF11377 is the first example of a high affinity peptide binding to a cytokine receptor as a cytokine antagonist.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | FEWTPGYWQPYALPL |
Sequence(3-letter code) | H-Phe-Glu-Trp-Thr-Pro-Gly-Tyr-Trp-Gln-Pro-Tyr-Ala-Leu-Pro-Leu-OH |
Peptide Structure |
|
Molecular Formula | C95H122N18O22 |
Molecular Weight | 1868.12 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: AF11377 ;171492-13-0;细胞因子(cytokine)拮抗剂多肽;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。