中文名：α-(4-哌啶基)二苯甲醇
英文名：Azacyclonol
英文别名：MER 17, MDL 4829;4-(Diphenylhydroxymethyl)piperidine
纯度：10mM in DMSO
货号：A408482
包装：1ml
Cas号：115-46-8
存储温度：-80℃储存
产品介绍：
Information
Azacyclonol (MER 17, MDL 4829), also known as γ-pipradol, is a drug used to diminish hallucinations in psychotic individuals.
In vitro
The formation of Azacyclonol in human intestinal microsomes is linear with respect to time up to 60 min. The rates of formation of Azacyclonol increases linearly with microsomal protein concentration up to 2 mg/mL. The apparent Km and Vmax values of Azacyclonol are 0.82 μM and 60 pmol/min/mg protein in microsomes from human liver. The formation of Azacyclonol and terfenadine alcohol from terfenadine is confirmed to be catalyzed predominantly by CYP3A(4) isozyme, and the ratio of the rate of terfenadine alcohol formation to that of Azacyclonol is 3:1. The amount of Azacyclonol eliminated renally increases on average 2-fold after rifampin dosing.
In vivo
Azacyclonol (i.v.) impairs the response of the nictitating membrane to both post- and preganglionic stimulation. The activity of Azacyclonol in depressing transmission through the cat superior ceivical ganglion is 6.63%.
Cell Data
cell lines：HCT116 cells and HCT116 TP53-/- cells
Concentrations：
Incubation Time：
Powder Purity:≥99%
查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/A408482.html
关键字： MER 17, MDL 4829;4-(Diphenylhydroxymethyl)piperidine
上海阿拉丁生化科技股份有限公司是A股上市公司（（股票代码：688179），专注于科研试剂的研发、生产和销售，已陆续建立多个工厂和研发中心。作为领军企业，阿拉丁始终坚持质量第一，连续13年被评为“最受欢迎试剂品牌”。
阿拉丁目前常备库存试剂产品品种超过7万种，SKU总数超过46万，产品线涵盖了化学试剂、生化试剂、药靶配体、蛋白质和抗体等多个领域，是国内少数化学试剂到生物试剂全面发展的国产试剂品牌，产品同步发布在我们国内（www.aladdin-e.com）和海外（www.aladdinsci.com）电商平台。