aladdin 阿拉丁 S164333 琥珀酰亚胺戊酸酯 PEG, mPEG-SVA MW 1000 Da

中文名：琥珀酰亚胺戊酸酯 PEG, mPEG-SVA

英文名：Succinimidyl valeric acid PEG, mPEG-SVA

纯度：MW 1000 Da

货号：S164333

包装：100mg、500mg

存储温度：-20°C储存

产品介绍：

N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol valeric acid (PEG-SVA) is an amino (-NH₂) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our succinimidyl valeric acid PEG (mPEG-SVA) offers superior reactivity yet higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.

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