USAG-1产品信息
英文名称:Sclerostin domain-containing protein 1
中文名称:含有硬化蛋白结构域的蛋白质-1
靶点别称:USAG-1
物种:Human
属性:Protein
标记:Unconjugated
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
USAG-1分子背景
USAG1(子宫致敏相关基因1),也称为SOSTDC1(含硬骨素结构域1),Ectodin,是一种分泌蛋白,其N端糖基化,C端半胱氨酸结结构域。这种C-末端半胱氨酸结结构域存在于多种生长因子中,包括TGFβ、NGF、PDGF、vWF、NDP和粘蛋白-2,并参与二聚化、受体结合和信号转导。SOSTDC1在细胞增殖、分化和凋亡的几个生物过程中负调控BMP信号传导(如牙形态发生、胚胎植入子宫内膜和骨折愈合)。此外,SOSTDC1还可能通过调节Wnt途径参与癌症的发展过程。
关键字: USAG-1;USAG-1蛋白;USAG-1重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。