Product Name：[Ser8]-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)
CAS No.：215777-46-1
Synonyms：胰高血糖素改造序列-Ser8
Catalog No.：153P06
Brand：HongTide（上海鸿肽生物）
Description：[Ser8]-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat)是GLP-1（7-36）的改造体多肽，N端第2个氨基酸（也就是完整序列1-37中的第8个氨基酸）Ala换成Ser。用丝氨酸替代丙氨酸显着提高了 GLP-1 (7-36) 酰胺对 DPP IV 的血浆稳定性，而不损害其促胰岛素活性。 这可能表明这种修饰可以提高 GLP-1 在治疗 II 型糖尿病中的潜力。
[Ser8]-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) is a modified peptide of GLP-1 (7-36), with Ala replacing the second amino acid at the N-terminus (i.e. the 8th amino acid in the complete sequence 1-37) with Ser. Replacing alanine with serine significantly improved the plasma stability of GLP-1 (7-36) amide on DPP IV without compromising its proinsulin activity. This may indicate that this modification can improve the potential of GLP-1 in the treatment of type II diabetes.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HSEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2 |
Sequence(3-letter code) | H-His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 |
Peptide Structure | ![[Ser8]-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) 215777-46-1.png](/SupplyImg1/2024-05-18/6385162266193919664019461.jpg "[Ser8]-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) 215777-46-1.png")
|
Molecular Formula | C149H226N40O46 |
Molecular Weight | 3313.68 |
订购联系方式：
上海鸿肽生物科技有限公司
手机： +86-18018095145 （同微信号）
QQ: 3259098395
邮箱：sales1@hongtide.com
关键字： [Ser8]-GLP-1 (7-36) ;215777-46-1;胰高血糖素改造序列-Ser8;多肽;多肽合成;
上海鸿肽生物科技有限公司（简称：鸿肽生物）是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖：定制多肽、目录多肽、氨基酸衍生物、小分子化合物；公司自成立以来，秉持“用质量作船， 以服务为帆，为科研服务”的企业理念，为国内外众多科研工作者提供了优质的服务及产品。