IL-1R1产品信息
别称:IL-1R1
物种:Human
属性:Protein
标记:Unconjugated
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
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IL-1R1分子背景
IL1R1也称为白细胞介素-1受体1型,是IL1A、IL1B和IL1RN的受体。与白细胞介蛋白-1结合后,与辅助受体IL1RAP结合形成高亲和力白细胞介素-1受体复合物,介导白细胞介导NF-kappa-B、MAPK和其他途径的白细胞介介素-1依赖性激活。信号传导涉及通过受体/共受体亚基的相应TIR结构域招募衔接分子,如TOLLIP、MYD88和IRAK1或IRAK2。以相当的亲和力结合配体,与拮抗剂IL1RN结合可防止与IL1RAP结合形成信号复合物。参与IL1B介导的T辅助1(Th1)细胞产生IFNG的共刺激。
![通用.jpg 通用.jpg](/SupplyImg1/2024-05-29/6385259896662985274211464.jpg)
关键字: IL-1R1;IL-1R1蛋白;IL-1R1重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。