Product Name:Cenderitide
CAS No.:507289-11-4
Synonyms:颗粒鸟酰基环化酶受体 (pGC) 激动剂多肽
Catalog No.:218P828
Brand:HongTide(上海鸿肽生物)
Description:Cenderitide 是一种有效的颗粒鸟酰基环化酶受体(pGC)激动剂多肽,是由37个氨基酸组成的多肽,包含两对二硫键。Cenderitide 是一种由 C 型利钠肽 (CNP) 与石斛利钠肽 (DNP) 的 C 端融合而成的利钠肽 (NP) 。Cenderitide 可激活 pGC-A 和 pGC-B,激活第二信使 cGMP,抑制醛固酮 (aldosterone),在不降低血压的情况下保持 GFR 。Cenderitide 可用于心力衰竭的研究。
Cenderitide is an effective particle guanoyl cyclase receptor (pGC) agonist peptide composed of 37 amino acids and containing two pairs of disulfide bonds. Cenderitide is a type of natriuretic peptide (NP) formed by fusing the C-terminus of C-type natriuretic peptide (CNP) and Dendrobium officinale natriuretic peptide (DNP). Cenderitide can activate pGC-A and pGC-B, activate the second messenger cGMP, inhibit aldosterone, and maintain GFR without lowering blood pressure. Cenderitide can be used for research on heart failure.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | GLSKGCFGLKLDRIGSMSGLGCPSLRDPRPNAPSTSA(Disulfide bridge:Cys6-Cys22) |
Sequence(3-letter code) | H-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Pro-Ser-Leu-Arg-Asp-Pro-Arg-Pro-Asn-Ala-Pro-Ser-Thr-Ser-Ala-OH(Disulfide bridge:Cys6-Cys22) |
Peptide Structure |
|
Molecular Formula | C158H263N49O50S3 |
Molecular Weight | 3745.27 |
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关键字: 507289-11-4;颗粒鸟酰基环化酶受体 (pGC) 激动剂;Cenderitide ;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。