描述/背景(Background)
The Claudin-18.2 (CLDN 18.2) protein, an isoform of Claudin 18, a member of the tight junction protein family, is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of various primary malignant tumors, such as gastric cancer/gastroesophageal junction (GC/GEJ) cancer, breast cancer, colon cancer, liver cancer, head and neck cancer, bronchial cancer and non-small-cell lung cancer. Claudin-18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified Claudin-18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors.
种属(Host Species)
Mouse
克隆号(Clone)
3B10
适用方法(Application)
IHC
效价(Property)
1:1000
状态(State)
Liquid
阳性对照(Positive Control)
Human Stomach Tissues
克隆类型(Clonality)
Monoclonal
分子别名(Synonym)
Claudin18.2, CLDN 18.2
研究领域(Research Field)
Cancer Drug Targets
抗体来源(Source)
同种型(Isotype)
IgG
储存(Storage)
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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