Human Nectin-4 Protein, His Tag
分子别名(Synonym)
NECTIN4,LNIR, PRR4, PVRL4
表达区间及表达系统(Source)
Human Nectin-4, His Tag (NE4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # Q96NY8-1).
Predicted N-terminus: Gly 32
蛋白结构(Molecular Characterization)
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This protein carries a polyhistidine tag at the C-terminus
The protein has a calculated MW of 36.0 kDa. The protein migrates as 40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
![2.jpg 2.jpg](/SupplyImg1/2024-07-02/6385553108367308128747449.jpg)
![3.jpg 3.jpg](/SupplyImg1/2024-07-02/6385553108838944736260819.jpg)
背景(Background)
Nectin-4(基因名PVRL4,脊髓灰质炎病毒受体样4)是一种66kDa的I型跨膜糖蛋白,属于Ig超家族蛋白的Nectin家族。凝集素是细胞粘附分子,在上皮细胞、内皮细胞、免疫细胞和神经元细胞的发育和成年生活中,在各种生物过程中发挥关键作用,如极性、增殖、分化和迁移。在50%、49%和86%的乳腺癌、卵巢癌和肺癌中,凝集素-4是一种肿瘤相关抗原,主要用于预后不良的肿瘤。在相应的正常组织中未检测到其表达。
关键字: Nectin-4;Nectin-4蛋白;Nectin-4重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。