Cynomolgus CEACAM-5 / CD66e Protein, His Tag (MALS verified)
分子别名(Synonym)
CEACAM-5,CD66e,CEA,Meconium antigen 100
表达区间及表达系统(Source)
Cynomolgus CEACAM-5, His Tag (CE5-C52H5) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Gly 685 (Accession # XP_005589491.1).
Predicted N-terminus: Gln 35
蛋白结构(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 73.6 kDa. The protein migrates as 100-170 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
癌胚抗原相关细胞粘附分子5(CEACAM5)也是癌胚抗原(CEA)、胎粪抗原100、CD抗原CD66e,CEACAM5属于免疫球蛋白超家族和CEA家族。CEACAM5含有七个Ig样(免疫球蛋白样)结构域。CEACAM5是一种同源二聚体蛋白,与大肠杆菌Dr粘附素结合导致同源二聚物解离。CEACAM5是细胞表面糖蛋白,在细胞粘附和细胞内信号传导中起作用。CEACAM5是E.coli Dr粘附素的受体。
关键字: CEACAM-5;CEACAM-5蛋白;CEACAM-5重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。