Human GAS6 (49-678) Protein, His Tag
分子别名(Synonym)
GAS6,GAS-6,AXLLG
表达区间及表达系统(Source)
Human GAS6 Protein, His Tag (GA6-H5246) is expressed from human 293 cells (HEK293). It contains AA Ala 49 - Ala 678 (Accession # Q14393-2).
蛋白结构(Molecular Characterization)
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 71.8 kDa. The protein migrates as 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
GAS6(生长停滞特异性蛋白6)也称为AXL受体酪氨酸激酶配体AXLLG。酪氨酸蛋白激酶受体AXL、TYRO3和MER的配体,其信号传导与细胞生长和存活、细胞粘附和细胞迁移有关。GAS6/AXL信号传导在各种过程中起着重要作用,如酸化过程中的内皮细胞存活,通过防止凋亡,人类自然杀伤细胞发育过程中的最佳细胞因子信号传导,肝再生,促性腺激素释放激素神经元存活和迁移,血小板活化或调节血栓反应。
关键字: GAS6;GAS6蛋白;GAS6重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。