Pleiotrophin产品信息
英文名称:Angiopoietin-related protein 4
中文名称:血管生成素相关蛋白4
靶点别称:Pleiotrophin,PTN
物种:Human
标签:His Tag
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human Pleiotrophin Protein, His Tag, premium grade (PLN-H5244) is expressed from E. coli cells. It contains AA Gly 33 - Asp 168 (Accession # P21246).
Predicted N-terminus: His
该产品是在我们严格的质量控制体系下生产的,该体系包含一套全面的测试,包括无菌和内毒素测试。在早期临床前阶段,产品性能经过仔细验证和测试,以确保其与细胞培养用途或任何其他应用的兼容性。当准备过渡到后期临床阶段时,我们还提供定制的GMP蛋白质服务,以满足您的需求。我们将与您合作,根据您的要求定制和开发GMP级产品,该产品也符合细胞疗法细胞制造中使用的原材料和辅助材料的要求。
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 17.2 kDa. The protein migrates as 22-23 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
内毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method.
无菌(Sterility)
Negative
支原体(Mycoplasma)
Negative.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
多效营养素和Midkine是结构上相关的肝素结合神经营养因子,其表达受发育调控。这些神经营养因子的表达模式表明其在神经发生、细胞迁移、次生器官发生诱导和中胚层上皮相互作用中起作用。PTN的表达在脑胚胎发生过程中增加,在出生时达到最大水平。PTN和Midkine的生理作用在很大程度上尚不清楚,但这些神经营养因子与神经母细胞瘤的发病机制有关。重组人多营养蛋白是一种15.4 kDa的蛋白质,含有136个氨基酸残基和5个分子内二硫键。
关键字: Pleiotrophin;PTN蛋白;多效生长因子;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。