Human TRDC Protein, His Tag
分子别名(Synonym)
TRDC
表达区间及表达系统(Source)
Human TRDC, His Tag (TRC-H52H4) is expressed from human 293 cells (HEK293). It contains AA Ser 1 - Val 129 (Accession # B7Z8K6-1).
蛋白结构(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 16.4 kDa. The protein migrates as 27-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
跨膜蛋白TCR由两条二硫键连接的多肽链组成:α和β链,γ和δ链。每条多肽链由一个可变区和一个恒定区组成。TRDC是T细胞受体(TCR)δ链的恒定区。它识别上皮边界经常表达的非肽抗原,这意味着激活γδT细胞的抗原大多是MHC非依赖性的。γδT细胞在人类和小鼠中具有广泛的功能,包括皮肤和粘膜上皮伤口修复、耐受诱导、细胞毒性和调节免疫反应的各种细胞因子的产生。
关键字: TRDC;TRDC蛋白;TRDC重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。