CCL4产品信息
英文名称:C-C motif chemokine 4
中文名称:趋化因子CCL4
靶点别称:CCL4,LAG1
物种:Human
标签:His Tag
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human CCL4 Protein, His Tag (CC4-H51H3) is expressed from E. coli cells. It contains AA Ala 24 - Asn 92 (Accession # P13236-1).
Predicted N-terminus: Met
蛋白结构(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 9.7 kDa.
制剂(Formulation)
Please contact us for detailed information.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
CCL4,也称为MIP-1β,是一种具有炎症和趋化动力学特性的单因子。与CCR5绑定。CD8+T细胞产生的主要HIV抑制因子之一。重组MIP-1β诱导对HIV-1、HIV-2和猿猴免疫缺陷病毒(SIV)不同毒株的剂量依赖性抑制。加工形式MIP-1-β(3-69)保留了诱导趋化因子受体CCR5表面表达下调和抑制CCR5介导的HIV-1进入T细胞的能力。MIP-1β(3-69)也是CCR1和CCR2亚型B的配体。
关键字: LAG1;LAG1蛋白;LAG1重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。