Molecular Formula:
C55H75N17O13
Relative Molecular Mass:
1182.31 g/mol
CAS-Number:
33515-09-2 (net), 34973-08-5 (acetate)
Long-term Storage:
-20 ± 5°C
Synonyms:
GnRH; Gonadotropin-Releasing Hormone; LHRH; Luliberin; Luteinizing Hormone-Releasing Factor
Sequence:
Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 acetate salt
Fields of Application:
Ovarian follicular cysts (veterinary medicine) Use in reproduction medicine Diagnosis of the hypothalamic-pituitary-gonadal axis function Cryptorchism Synchronization of ovulation (veterinary medicine)
Active Substance:
Gonadorelin, also known as GnRH or LHRH, is produced by neuroendocrine cells within the hypothalamus. The hormone is secreted pulsatilely. Gonadorelin induces the release of LH and FSH from the anterior pituitary. After a transient increase, continuous administration of gonadorelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis
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