P6897-1mg
Recombinant Rat VCC-1/CXCL17
1mg
15611.00元
Species
Gene ID
Accession
Source
Length
MW
Tag
Rat
308436
D4A875
E. coli
97aa
11.5kDa
－
Name
Recombinant Rat VCC-1/CXCL17 (Recombinant Rat VEGF Co-regulated Chemokine 1/CXCL17; rRtVCC-1/CXCL17)；重组大鼠血管内皮生长因子联合调节趋化因子1/CXCL17
Synonyms
CXCL17; DMC; VCC-1; Chemokine (C-X-C Motif) Ligand 17; C-X-C Motif Chemokine 17; Dcip1; Dendritic Cell And Monocyte Chemokine-Like Protein; DMC; UNQ473; VCC1; VCC-1; VEGF Coregulated Chemokine 1; VEGF Co-Regulated Chemokine 1
Purity
>97% by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0μg/ml, corresponding to a specific activity of >200IU/mg
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in 2X PBS, pH7.4.
Endotoxin
Less than 1EU/μg of rRtVCC-1/CXCL17 as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
Background
CXCL17 also named Dendritic Cell and Monocyte Chemokine-like Protein (DMC) and VEGF Co-regulated Chemokine 1 (VCC-1), is a small cytokine belonging to the CXC chemokine family. It is constitutively expressed in the lung and can be detected in trachea, stomach and skeletal muscle. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It may be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues and may play a role in the innate defense against infections. Mature human CXCL17 shares 73%, 71% and 64% amino acid sequence identity with bovine, mouse and rat DMC, respectively.
Amino Acid Sequence
SPNQEVARHH GDQHQAPRRW LWEGGQECDC KDWSLRVSKR KTTAVLEPPR KQCPCDHVKG SEKKNRRQKH HRKSQRPSRT CQQFLKRCQL ASFTLPL
包装清单:
P6897-2μg
Recombinant Rat VCC-1/CXCL17
2μg
P6897-10μg
Recombinant Rat VCC-1/CXCL17
10μg
P6897-100μg
Recombinant Rat VCC-1/CXCL17
100μg
P6897-1mg
Recombinant Rat VCC-1/CXCL17
1mg
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
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