P6857-1mg
Recombinant Rat CINC-3/CXCL2
1mg
15444.00元
Species
Gene ID
Accession
Source
Length
MW
Tag
Rat
114105
P30348
E. coli
73aa
7.9kDa
－
Name
Recombinant Rat CINC-3/CXCL2 (Recombinant Rat Cytokine-induced Neutrophil Chemoattractant 3/CXCL2; rRtCINC-3/CXCL2)；重组大鼠中性粒细胞趋化因子3/CXCL2
Synonyms
CINC-3; GRO beta; MGSA-beta; MIP-2; chemokine (C-X-C motif) ligand 2; CINC-2a; C-X-C Motif Chemokine 2; GRO2; GRO2 oncogene; GROb; GROB; gro-beta; Gro-beta; Growth-regulated protein beta; Macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; MGSA beta; MGSA-b; MIP2; MIP2A; MIP-2a; MIP2-alpha; SCYB2
Purity
>98% by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using rat neutrophils is in a concentration range of 10-100ng/ml.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.
Endotoxin
Less than 1EU/μg of rRtCINC-3/CXCL2 as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
Background
Rat CXCL2 also named CINC-3, belongs to the CXC chemokine family. It is encoded by the gene CXCL2 and shares 90% amino acid sequence with CXCL1/GROα. It is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is expressed by cytokine-stimulated rat alveolar macrophages and fibroblasts. The functional receptor for CXCL2 has been identified as CXCR2. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. Similar to other GRO proteins, CXCL2 is potent neutrophil attractants and activators. In addition, it is also active toward basophils. The amino acid sequence of rat CXCL2 is 88% identical to murine CXCL2.
Amino Acid Sequence
VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN
包装清单:
P6857-5μg
Recombinant Rat CINC-3/CXCL2
5μg
P6857-25μg
Recombinant Rat CINC-3/CXCL2
25μg
P6857-100μg
Recombinant Rat CINC-3/CXCL2
100μg
P6857-1mg
Recombinant Rat CINC-3/CXCL2
1mg
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
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