| 产品编号 |
产品名称 |
产品包装 |
产品价格 |
| P5588-1mg |
Recombinant Human HB-EGF |
1mg |
7722.00元 |
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Human
|
1839
|
Q99075
|
E. coli
|
86aa
|
9.7kDa
|
－
|
|
About this Antibody
|
|
Name
|
Recombinant Human HB-EGF (Recombinant Human Heparin-binding EGF-like Growth Factor; rHuHB-EGF)；重组人肝素结合表皮生长因子样生长因子
|
|
Synonyms
|
Dtr; Dts; Hegfl; diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor); DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor); DTS; DTSF; heparin-binding EGF-like growth factor; heparin-binding epidermal growth factor; proheparin-binding EGF-like growth factor
|
|
Purity
|
>97% by SDS-PAGE and HPLC analyses.
|
|
Biological Activity
|
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1ng/ml, corresponding to a specific activity of >1.0×106IU/mg.
|
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 130mM NaCl.
|
|
Endotoxin
|
Less than 1EU/μg of rHuHB-EGF as determined by LAL method.
|
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
|
Category
|
Cytokine
|
|
Background
|
Heparin-binding epidermal growth factor (HB-EGF)-like growth factor (EGF) is found in cerebral neurons. Its expression is increased after hypoxic or ischemic injury, which also stimulates neurogenesis. HB-EGF has been implicated as a participant in a variety of normal physiological processes such as blastocyst implantation, wound healing, and in pathological processes such as tumor growth, SMC hyperplasia and atherosclerosis. HB-EGF is an 87 amino acid mitogenic and chemotactic glycoprotein containing an EGF-like domain with six conserved cysteine residues. Human HB-EGF shares about 73% and 76%a.a. sequence identity with murine and rat HB-EGF.
|
|
Amino Acid Sequence
|
DLQEADLDLL RVTLSSKPQA LATPNKEEHG KRKKKGKGLG KKRDPCLRKY KDFCIHGECK YVKELRAPSC ICHPGYHGER CHGLSL
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
P5588-10μg
|
Recombinant Human HB-EGF
|
10μg
|
|
P5588-50μg
|
Recombinant Human HB-EGF
|
50μg
|
|
P5588-100μg
|
Recombinant Human HB-EGF
|
100μg
|
|
P5588-1mg
|
Recombinant Human HB-EGF
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。