| 产品编号 |
产品名称 |
产品包装 |
产品价格 |
| P7253-5μg |
Recombinant Human Bcl-w |
5μg |
464.00元 |
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Human
|
599
|
Q92843
|
E. coli
|
171aa
|
18.6kDa
|
－
|
|
About this Antibody
|
|
Name
|
Recombinant Human Bcl-w (Recombinant Human Bcl-w; rHuBcl-w)；重组人B细胞淋巴瘤w
|
|
Synonyms
|
BCL2L2; Apoptosis regulator Bcl-W; Bcl2-L-2; BCL2-like 2; BCL-W; BCLWbcl-2-like protein 2; KIAA0271BCL2-L-2
|
|
Purity
|
>95% by SDS-PAGE and HPLC analyses.
|
|
Biological Activity
|
Test in Process.
|
|
Physical Appearance
|
Sterile Filtered lyophilized (freeze-dried) liquid-like powder.
|
|
Formulation
|
0.2μm filtered concentrated solution in 25mM Hepes, pH7.4, 100mM KCl, 10% Glycerol, 5% Trehalose, 0.02% Tween-80.
|
|
Endotoxin
|
Less than 1EU/μg of rHuBcl-w as determined by LAL method.
|
|
Reconstitution
|
N/A
|
|
Category
|
Others
|
|
Background
|
Bcl-w, also named as BCL2L2, belongs to the Bcl-2 family and is encoded by the BCL2L2 gene in human. Bcl-w is expressed in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands, and moderate levels in thymus, ovary and small intestine. It is also expressed in cell lines of myeloid, fibroblast and epithelial origin. Bcl-w is an anti-apoptotic (pro-survival) protein that reduces cell apoptosis under cytotoxic conditions. Mature human Bcl-w shares 98%-99% amino acid sequence identity with murine, bovine, canine Bcl-w.
|
|
Amino Acid Sequence
|
ATPASAPDTR ALVADFVGYK LRQKGYVCGA GPGEGPAADP LHQAMRAAGD EFETRFRRTF SDLAAQLHVT PGSAQQRFTQ VSDELFQGGP NWGRLVAFFV FGAALCAESV NKEMEPLVGQ VQEWMVAYLE TQLADWIHSS GGWAEFTALY GDGALEEARR LREGNWASVR T
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
P7253-5μg
|
Recombinant Human Bcl-w
|
5μg
|
|
P7253-25μg
|
Recombinant Human Bcl-w
|
25μg
|
|
P7253-100μg
|
Recombinant Human Bcl-w
|
100μg
|
|
P7253-1mg
|
Recombinant Human Bcl-w
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品在冻干时添加了海藻糖作为保护剂，此时冻干后本产品看起来仍然像是液体，属于正常现象。在冻干工艺上，海藻糖作为常用的冻干保护剂，可显著阻止蛋白质二级结构的改变，防止冻干过程中的蛋白变性。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。