产品编号 |
产品名称 |
产品包装 |
产品价格 |
P5340-1mg |
Recombinant Human BAFF Receptor/TNFRSF13C |
1mg |
7722.00元 |
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
Human
|
115650
|
Q96RJ3
|
E. coli
|
76aa
|
7.8kDa
|
-
|
About this protein
|
Name
|
Recombinant Human BAFF Receptor/TNFRSF13C (Recombinant Human B Cell Activating Factor Receptor; rHuBAFF-R);重组人B细胞激活因子受体/TNFSF13C
|
Synonyms
|
BR3; CD268; TNFRSF13C
|
Purity
|
>95% by reduced SDS-PAGE analyses.
|
Biological Activity
|
Fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0μg/ml in the presence of 1.0μg/ml of rHuBAFF.
|
Physical Appearance
|
Sterile Filtered White lyophilized (freeze-dried) powder.
|
Formulation
|
Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH8.0, 500mM NaCl.
|
Endotoxin
|
Less than 1EU/μg of rHuBAFF-R as determined by LAL method.
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
|
Category
|
Cytokine
|
Background
|
B Cell Activating Factor Receptor (BAFF-R), also named tumor necrosis factor receptor superfamily member 13C, is a member of the TNFR superfamily. It is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF receptor is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain and binds with high specificity to BAFF (TNFSF13B). It enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF receptor/BAFF signaling plays a critical role in B cell survival and maturation.
|
Amino Acid Sequence
|
MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
|
包装清单:
产品编号
|
产品名称
|
包装
|
P5340-10μg
|
Recombinant Human BAFF Receptor/TNFRSF13C
|
10μg
|
P5340-50μg
|
Recombinant Human BAFF Receptor/TNFRSF13C
|
50μg
|
P5340-100μg
|
Recombinant Human BAFF Receptor/TNFRSF13C
|
100μg
|
P5340-1mg
|
Recombinant Human BAFF Receptor/TNFRSF13C
|
1mg
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。