Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3.
温馨提示:TSU-68 (Orantinib, SU6668),品质稳定,纯度>98+%,仅供实验使用.产品质量严格控制,保证品质。
南京百鑫德诺生物科技有限公司
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