丙磺舒钠

convert probenecid into a water-soluble salt when combined with penicillins for injection to form a compound injection, and usually into probenecid sodium, which is easily soluble in water. Probenecid sodium, probenecid potassium and β-lactam antibiotics constitute a compound target agent and its use, which can reduce the amount of β-lactam antibiotics in the compound, thereby effectively reducing bacterial resistance caused by ultra-high doses of antibiotics. The occurrence and development of drugs; it can also save antibiotic resources and reduce the abuse of antibiotics; probenecid sodium (potassium) and β-lactam antibiotics, including penicillin antibiotics and cephalosporin antibiotics, form powder injections and freeze-dried powder injections. It is intravenously or intravenously infused at the same time as β-lactam antibiotics. It can effectively prolong the half-life (t1/2) of β-lactam antibiotics, increase the area under the curve (AUC), and at the same time eliminate the hemolysis of probenecid sodium (potassium). The safety of the human body plays a protective role, and it can be safely and effectively used as a new compound preparation to enter the human body through the intravenous route; a compound drug composed of probenecid sodium (potassium) and β-lactam antibiotics, because Directly into the blood circulation, the body absorbs completely, can reach the peak quickly, the effect is rapid, and the curative effect is more significant.

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