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生物化工
抗体
ANTI-ITB1 POLYCLONAL ANTIBODY
Anti-ITB1 Polyclonal Antibody
Anti-ITB1 Polyclonal Antibody
价格
¥
1600.00
¥
960.00
包装
100ul
50ul
最小起订量
50ul
发货地
北京
更新日期
2024-09-13
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产品详情
中文名称:
Anti-ITB1 Polyclonal Antibody
英文名称:
Anti-ITB1 Polyclonal Antibody
Gene ID:
16412
Public Immunogen Range:
A synthetic peptide of human ITB1
Subcellular Locations:
Plasma membrane Endosome
Swiss Prot:
P09055
保存:
Store at -20°C. Avoid freeze / thaw cycles.
别名:
AC;ACDase;ASAH;PHP;PHP32;SMAPME
产品编号:
K101537P
储存液:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法:
Affinity purification
蛋白分子量:
88kDa
交叉反应:
Mouse
克隆类型:
Polyclonal Antibody
免疫原:
A synthetic peptide of human ITB1
品牌:
solarbio
宿主:
Rabbit
稀释比例:
WB 1:5000.
性状:
液体
亚型:
IgG
应用:
WB
英文名称:
Anti-ITB1 Polyclonal Antibody
2024-09-13
Anti-ITB1 Polyclonal Antibody
Anti-ITB1 Polyclonal Antibody
100ul/1600.00RMB;50ul/960.00RMB
1600.00
背景资料
Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (By similarity). ITGA4:ITGB1 and ITGA5:ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (By similarity). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity).
关键字:
Anti-ITB1 Polyclonal Antibody;抗体
公司简介
北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验室专用设备、办公用品、化工产品(不含危险化学品)、计算机软件及辅助设备;货物进出口、技术进出口、代理进出口;委托加工生产生物制品、生化制品、化工产品(不含危险化学品);生产生物试剂盒;批发第一类医疗器械、第二类医疗器械;批发第三类医疗器械。
成立日期
2004-09-22
(20年)
注册资本
1000万元
员工人数
50-100人
年营业额
¥ 500万-1000万
主营行业
分析化学,生物化工,化学试剂,医药原料,仪器耗材
经营模式
贸易,工厂,试剂
北京索莱宝科技有限公司
VIP
9年
公司成立:
20年
注册资本:
1000万元
企业类型:
有限责任公司
主营产品:
tris,甘氨酸,琼脂粉,潮霉素B,SDS,BSA
公司地址:
联东U谷景盛南四街85A三层
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