Anti-ICAM1 antibodyCat. No. JC261536
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-ICAM1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human ICAM1
Reactivity Human
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
![](https://img1.dxycdn.com/2019/0117/424/3323665649704001914-14.png)
Target information
Symbol ICAM1
Full name intercellular adhesion molecule 1
Synonyms BB2; CD54; P3.58
Swissprot P05362
Target Background
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Anti-ICAM1 antibodyApplications
Immunohistochemistry
Predicted cell location: Cytoplasm and membrane
Positive control: Human lung cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm and membrane
Positive control: Human breast cancer
Recommended dilution: 50-200
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