Anti-DMAP1 antibodyCat. No. JC163722
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-DMAP1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human DMAP1
Reactivity Human, Mouse
Content 0.54 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-DMAP1 antibodyTarget information
Symbol DMAP1
Full name DNA methyltransferase 1 associated protein 1
Synonyms EAF2; SWC4; MEAF2; DNMAP1; DNMTAP1
Swissprot Q9NPF5
Target Background
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Anti-DMAP1 antibodyApplications
Immunohistochemistry
Predicted cell location: Cytoplasm or Nucleus
Positive control: Human gastric cancer
Recommended dilution: 20-100 Predicted cell location: Cytoplasm or Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 20-100