Product name
IL1RN Polyclonal Antibody
Isotype
IgG
Form
Lyophilized or Liquid
Tested applications
WB,IF,ELISA,IHC
Species reactivity
Human,Mouse
Host Species
Rabbit
Purity
Affinity purification
Immunogen Information：
Immunogen
Recombinant protein of human IL1RN
Calculated molecular weight
16kDa/17kDa/19kDa/20kDa
Observed molecular weight
23kDa
Swiss Prot
P18510
Gene ID (NCBI)
3557
Alternative Names
DIRA;ICIL-1RA;IL-1ra;IL-1ra3;IL-1RN;IL1F3;IL1RA;IRAP;MVCD4
Application Notes：
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
1:500 - 1:2000
IF
1:50 - 1:200
IHC
1:50 - 1:500
Western blot analysis of extracts of various cell lines, using IL1RN antibody.
Immunofluorescence analysis of MCF-7 cells using IL1RN antibody.
Background：
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Storage：
Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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