左氧氟沙星

Product name

Levofloxacin hemihydrate

CAS NO.

100986-85-4

M.F.

C₁₈H₂₀FN₃O₄

M.W

361.373

Structure

EINECS

600-146-0

Chemical Properties

Melting point

218 °C

Density

1.48g/cm³

Boiling point

571.5°Cat760mmHg

Flash point

299.4°C

Safety information

Package

Net weight

25kgs/drum

Gross weight

27.5kgs

Certificate

GMP, AFM, registration in Korea

Appearance

Light yellowish-white to yellow-white crystals or crystalline powder

Assay
(on the anhydrous basis)

98.5-102.0%

Residue on ignition

NMT 0.2%

Heavy metals

NMT 10ppm

Organic impurities

N-Desmethyl levofloxacin NMT 0.3%

Diamine derivative NMT 0.3%

Levofloxacin N-oxide NMT 0.3%

9-Desfluoro levofloxacin NMT 0.3%

D-Isomer NMT 0.1%

Any unknown impurity

NMT 0.1%

Total impurities

NMT 0.5%

Optical rotation at 20 °C

-920~ -1060

Water

2.1% ~2.7%

Residual solvents

Chloroform

NMT 60ppm

Ethanol

NMT 1000ppm

DMSO

NMT 1000ppm